Integrating Life Sciences and Mechanics in Bio-engineering Context
This research project deals with the area of Cellular Biomechanics. The objectives of the research are to characterize the mechanical properties of bio cells including obtaining a better understanding of their adhesion properties. A Virtual Reality based simulation environment will also be created to enable further study of these issues. An Information Based Manufacturing (INBM) framework is also being developed with the target domain identified as "the manipulation of bio cells." While at first glance, the domain of "cell manipulation" seems to posses no similarities to manufacturing / engineering, our work seeks to infuse engineering / manufacturing ideas in the creation of a collaborative framework in this bio engineering context; our prior work in the assembly of micro devices (LIGA parts) will enable us to lay the foundation for a test bed in the area of bio cell manipulation. Through the development of mechanical models, future research can focus on developing innovative methods to stimulate cell growth and formation of tissues which are critical to many emerging research areas. The research findings will provide a significant advancement in the understanding of the mechanical behavior of cells.
Modeling the role of adhesive forces during cell manipulation